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Ferric Gluconate is Highly Efficacious in Anemic Hemodialysis Patients with High
Serum Ferritin and Low Transferrin Saturation: Results of the Dialysis Patients’
Response to IV Iron with Elevated Ferritin (DRIVE) Study
Daniel W. Coyne, Toros Kapoian, Wadi Suki, Ajay K. Singh, John E. Moran, Naomi V.
Dahl, Adel R. Rizkala, and the DRIVE Study Group
J Am Soc Nephrol. 2007;18:975-984.
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REFERENCES
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Important Safety Information3
Ferrlecit® is indicated for the treatment of iron deficiency anemia in chronic
hemodialysis patients age 6 years and over receiving supplemental epoetin therapy
• Ferrlecit® is contraindicated in non iron-deficient anemias, in patients
hypersensitive to Ferrlecit® or its inactive components, or with evidence of
iron overload • Hypersensitivity reactions have been reported with injectable
iron products • Hypotension has been reported with rapid administration of
IV iron • In a single-dose, placebo-controlled safety study (n=1097), the most
frequent adverse events occurring after Ferrlecit® administration were hypotension,
nausea, and vomiting and/or diarrhea • In multiple-dose studies (n=126), the
most frequent adverse events, whether or not related to Ferrlecit® administration
were nausea, vomiting and/or diarrhea, injection site pain, hypotension, cramps,
hypertension, dizziness, dyspnea, and chest pain
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